Vitamin D Status And Parathyroid Hormone In Albanians

Abstract

VitaminD is a fat soluble organic compound, acting like a hormone and playing acrucial role in calcium homeostasis in the human body. Both vitamin D andparathyroid hormone are essential in calcium metabolism. This paper aims theassessment of the current situation of vitamin D status and parathyroid hormonein Albanians, during the period of time from 2009 to 2014. All the individualsinvolved in this study were taken under examination through blood sampling (10ml/person) to check for the present value of vitamin D and PTH as well as otherparameters, such as calcium, phosphate, etc. PTH and vitamin D levels weremeasured by electrochemiluminescence immunoassay, while total calcium andphosphate values were measured by Turbidimetry method on Coobas 6000 system.The values of 25(OH) D and PTH were correlated with age, gender andelectrolytes. From the results, we notice a high prevalence of vitamin Dinsufficiency in the group with primary hyperparathyroidism (18.15±8.75 ng/ml),low levels of vitamin D in the group with secondary hyperparathyroidism(15.71±4.45 ng/ml) and in the group with hypoparathyroidism (15.83±9.31 ng/ml).We noticed also a negative correlation between 25(OH) D and PTH levels. Inconclusion, we can say that, from this study, it is noticed a high prevalenceof vitamin D deficiency in Albanians, and we can recommend regular blood testsat a certain age, in order to prevent other diseases linked to low levels orinsufficiency of vitamin D.